N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide

CAS: 90357-51-0

Ref. TR-C987585

Product Information

• Name: N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide
• Synonyms: Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl- (9CI), 2-Methyloxirane-2-carboxylic acid N-(4-cyano-3-trifluoromethylphenyl)amide, Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-, (±)-
• Brand: TRC
• Description: Impurity Bicalutamide Oxirane Impurity / Bicalutamide Epoxide ImpurityApplications N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide, is an intermediate in synthesis of more complex pharmaceutical compounds. It is used in the synthesis of potential impurities of Bicalutamide (B382000), which is an oral nonsteroidal, anti-androgen drug used for prostate cancer.References Nandu Baban, B., et al.: Synthetic Communications, 39, 1516 (2009)

Chemical properties

• Molecular weight: 270.21
• Formula: C₁₂H₉F₃N₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C12H9F3N2O2/c1-11(6-19-11)10(18)17-8-3-2-7(5-16)9(4-8)12(13,14)15/h2-4H,6H2,1H3,(H,17,18)
• InChI key: InChIKey=GPGKZPUNVOBAKA-LLVKDONJSA-N
• SMILES: C[C@]1(C(=O)Nc2ccc(C#N)c(C(F)(F)F)c2)CO1