D-Cycloserine

CAS: 68-41-7

Ref. TR-C988815

Product Information

• Name: D-Cycloserine
• Synonyms: Cycloserine, 3-Isoxazolidinone, 4-amino-, (4R)-, 3-Isoxazolidinone, 4-amino-, (+)- (8CI), 3-Isoxazolidinone, 4-amino-, (R)-, (+)-Cycloserine, (4R)-4-Amino-3-isoxazolidinone, (R)-(+)-Cycloserine, (R)-4-Amino-3-isoxazolidinone, (R)-Cycloserine, Closerin, Closina, Cyclo-D-serine, Cyclorin, D-4-Amino-3-isoxazolidinone, D-4-Amino-3-isoxazolidone, D-CS, Farmiserina, Micoserina, Miroseryn, NSC 154851, NSC 76029, Novoserin, Orientomycin, Oxamycin, PA 94, Seromycin, Tisomycin, Wasserina, d-4-Amino-3-isoxazolidinone, Cycloserine
• Brand: TRC

Description

Applications D-Cycloserine inhibits cell wall biosynthesis (D-Ala peptide bond formation). D-Cycloserine also prevents conversion of D-Ala to L-Ala. D-Cycloserine is an bacteriostatic. D-Cycloserine is an antibiotic against Gram-negative bacteria. There is evidence that D-cycloserine can enhance neuronal changes that lead to learning.
References Lamb., J.W., et al.: Anal. Profiles Drug Subs., 1, 53 (1972), Gentry-Weeks, C., et al.: J. Biol. Chem., 268, 7298 (1993), Alexander, F., et al.: Eur. J. Biochem., 219, 953 (1994), Auger, S., et al.: Biochimie, 87, 231 (2005); Chem and Eng. News p. 12, Dec. 7/14 (2015)

Chemical properties

• Molecular weight: 102.09
• Formula: C₃H₆N₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
• InChI key: InChIKey=DYDCUQKUCUHJBH-UWTATZPHSA-N
• SMILES: N[C@@H]1CONC1=O