Product Information
Name:(S)-Ruxolitinib
Controlled Product
Synonyms:
- (3S)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile (ent-Ruxolitinib)
- (3S)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile
Brand:TRC
Description:Applications (3S)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile is a newly developed JAK2 inhibitor therapy aimed to improve MPN-associated splenomegaly and systemic symptoms. The opposite enantiomer of Ruxolitinib (R702000).References Koppikar, P., et al.: Nature., 489, 155 (2012); Ratcliffe, A.J., et al.: Drug. Discover. Series., 19, 218 (2012);
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Chemical properties
Molecular weight:306.36
Formula:C17H18N6
Color/Form:Neat
InChI:InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m0/s1
Technical inquiry about: (S)-Ruxolitinib
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