Cyproterone-d4

CAS: 2098-66-0

Ref. TR-C989092

Product Information

• Name: Cyproterone-d4
• Synonyms: 6-Chloro-6-dehydro-17a-hydroxy-1,2a-methyleneprogesterone-d4, 6-Chloro-17-hydroxy-1a,2a-methylenepregna-4,6-diene-3,20-dione-d4, 1,2a-Methylene-6-chloro-6-17a-hydroxyprogesterone-d4, (1ß,2ß)-6-Chloro-1,2-dihydro-17-hydroxy-3'H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione-d4, (1R,3aS,3bR,7aR,8aS,8bS,8cS,10aS)-1-acetyl-5-chloro-1-hydroxy-8b,10a-dimethyl-2,3,3a,3b,7a,8,8a,8b,8c,9,10,10a-dodecahydrocyclopenta[a]cyclopropa[g]phenanthren-7(1H)-one, (1R,7aR,8aS)-1-acetyl-5-chloro-1-hydroxy-8b,10a-dimethyl-2,3,3a,3b,7a,8,8a,8b,8c,9,10,10a-dodecahydrocyclopenta[a]cyclopropa[g]phenanthren-7(1H)-one, (1R,7aR,8bS,10aS)-1-acetyl-5-chloro-1-hydroxy-8b,10a-dimethyl-2,3,3a,3b,7a,8,8a,8b,8c,9,10,10a-dodecahydrocyclopenta[a]cyclopropa[g]phenanthren-7(1H)-one, (1β,2β)-6-Chloro-1,2-dihydro-17-hydroxy-3′H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 1,2α-Methylene-6-chloro-⁶-17α-hydroxyprogesterone, 3'H-Cyclopropa(1,2)pregna-1,4,6-triene-3,20-dione, 6-chloro-1-beta,2-beta-dihydro-17-hydroxy-, 3′H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 6-chloro-1,2-dihydro-17-hydroxy-, (1β,2β)-, 3′H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 6-chloro-1β,2β-dihydro-17-hydroxy-, 6-Chlor-delta(sup 6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteron, 6-Chlor-delta(sup 6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteron [German], 6-Chloro-1,2α-methylene-4,6-pregnadien-17α-ol-3,20-dione, 6-Chloro-17-hydroxy-1α,2α-methylenepregna-4,6-diene-3,20-dione, 6-Chloro-6-dehydro-17α-hydroxy-1,2α-methyleneprogesterone, Bay 94-8367, Bay94-8367, Ciproterona, Ciproterona [INN-Spanish], Ciproterone, Ciproterone [DCIT], Cyproteron, Cyproterone [INN:BAN], Cyproteronum, Cyproteronum [INN-Latin], Pregna-4,6-diene-3,20-dione, 6-chloro-17-hydroxy-1α,2α-methylene-, Sh 80881, Sh 881, Unii-E61Q31Ek2F

Description

Applications Labelled Cyproterone (C989090). An antiandrogen, suppresses Testosterone and its metabolites. Derivatives of Cyproterone are administered to patients suffering from hypersexuality and to help facilitate the sexual transformation of male-to-female transsexuals.
References Gracia, T., et al.: Toxicol. App. Pharmacol., 225, 142 (2007), Ahlin, G., et al.: J. Med. Chem., 51, 5932 (2008), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Bovee, T., et al.: J. Steroid Biochem. Mol. Biol., 118, 85 (2010),

• Brand: TRC

Chemical properties

• Molecular weight: 378.93
• Formula: C₂₂H₂₃D₄ClO₃
• Color/Form: Neat
• InChI: InChI=1S/C22H27ClO3/c1-11(24)22(26)7-5-14-12-9-18(23)17-10-19(25)13-8-16(13)21(17,3)15(12)4-6-20(14,22)2/h9-10,12-16,26H,4-8H2,1-3H3/t12-,13+,14-,15-,16-,20-,21-,22-/m0/s1/i1D3,10D
• InChI key: InChIKey=DUSHUSLJJMDGTE-PERGGGDWSA-N
• SMILES: [2H]C1=C2C(Cl)=C[C@@H]3[C@H](CC[C@@]4(C)[C@H]3CC[C@]4(O)C(=O)C([2H])([2H])[2H])[C@@]2(C)[C@H]2C[C@H]2C1=O