5,​5-​Dioxide Thioridazine Disulfoxide

CAS: 100574-22-9

Ref. TR-D100575

Product Information

• Name: 5,​5-​Dioxide Thioridazine Disulfoxide
• Synonyms: 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)-10H-phenothiazine 5,5-Dioxide, Sulforidazine 5-Sulfone, Thioridazine Hydrochloride Imp. A (EP), Thioridazine Imp. A (EP), Thioridazine Hydrochloride Impurity A, Thioridazine Impurity A
• CAS: 100574-22-9

Description

Applications 5,​5-​Dioxide Thioridazine Disulfoxide is the impurity of Thioridazine Hydrochloride (T368800). Thioridazine HCl is a dopamine receptor blocker and antipsychotic. It is the parent compound of sulforidazine and mesoridazine. This compound has been reported to bind strongly to dopamine receptors on cancer stem cells and cause differentiation leaving normal cells alone.
References Goldenthal, E.I., Toxicol. Appl. Pharmacol., 18, 185 (1971), Abdel-Moety, E.M., et al.: Anal. Profile Drug Subs., 18, 459 (1989),

• Brand: TRC

Chemical properties

• Molecular weight: 434.57
• Formula: C₂₁H₂₆N₂O₄S₂
• Color/Form: Neat
• InChI: InChI=1S/C21H26N2O4S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)29(26,27)21-11-10-17(15-19(21)23)28(2,24)25/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3
• InChI key: InChIKey=YECWCJHGQWLNLB-UHFFFAOYSA-N
• SMILES: CN1CCCCC1CCN1c2ccccc2S(=O)(=O)c2ccc(S(C)(=O)=O)cc21