Product Information
Name:Dacomitinib
Controlled Product
Synonyms:
- 2-Butenamide
- N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-
- (2E)-
- (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamide
- PF 00299804
- PF 299
- PF 299804
Brand:TRC
Description:Applications Dacomitinib is an Erb-inhibitor, or an inhibitor of the members of the epidermal growth factor receptor family. Used as an ant-cancer agent due to observation of over-expressed epidermal growth factor receptor in nearly all cases of squamous cell carcinoma in the head and neck.References Williams, J. et al.: PLoS., 9, e98557 (2014); Peters, S. et al.: Canc. Treatment Rev., 40, 917 (2014);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:469.94
Formula:C24H25ClFN5O2
Color/Form:Neat
InChI:InChI=1S/C24H25ClFN5O2/c1-33-22-14-20-17(24(28-15-27-20)29-16-7-8-19(26)18(25)12-16)13-21(22)30-23(32)6-5-11-31-9-3-2-4-10-31/h5-8,12-15H,2-4,9-11H2,1H3,(H,30,32)(H,27,28,29)/b6-5+
InChI key:InChIKey=ATVQZEZXTPHWTH-WTYVYLTKSA-N
SMILES:CCCCCCCC1(CC[C@H]2[C@@H](O)CC3OC(=O)C[C@H]32)OCCO1
Technical inquiry about: Dacomitinib
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