DAMGO

CAS: 78123-71-4

Ref. TR-D134600

Product Information

• Name: DAMGO
• Synonyms: [D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin, 158: PN: US20030176421 PAGE: 54-55 Caimed Protein TFA Salt, 3: PN: WO2009046859 PAGE: 98 Claimed Protein DAGO TFA Salt, DAGOL TFA Salt, DAMGE TFA Salt, DAMGO TFA Salt, DAMPGO TFA Salt, H-Tyr-D-Ala(Me)Phe-NH-CH2-OH NIH 10891 TFA Salt, RX 783006 TFA Salt, Tyr-D-Ala-Gly-(methyl)Phe-Gly-ol TFA Salt, Tyr-D-Ala-Gly-MePhe-Gly-ol TFA Salt, Tyr-D-Ala-Gly-MePhe-NH-(CH2)2OH TFA Salt, Tyr-D-Ala-Gly-N-methylphenylalanine-glycinol TFA Salt
• Brand: TRC
• Description: Stability HygroscopicApplications DAMGO is an opioid receptor agonist (1,2). DAMGO can be used to investigate the analgesic mechanism of opioids. It has been shown that DAMGO can modulate the two-pore domain K(+) channels in the substantia gelatinosa neurons (3).References (1) Talmont, F. et al.: Peptide., 55, 79 (2014) (2) Trigub, M. et al.: Bull. Exp. Biol. Med., 156, 778 (2014) (3) Cho, P. S., et al.: Korean J Physiol Pharmacol. 20, 525 (2016)

Chemical properties

• Molecular weight: 513.5911402
• Formula: C₂₆H₃₅N₅O₆•x(C₂HF₃O₂)
• Color/Form: Neat
• InChI: InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1
• InChI key: InChIKey=HPZJMUBDEAMBFI-WTNAPCKOSA-N
• SMILES: C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO