DAMPA

CAS: 19741-14-1

Ref. TR-D136500

Product Information

• Name: DAMPA
• Synonyms: Benzoic acid, 4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]-, Benzoic acid, p-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]- (6CI,8CI), 4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoic acid, 2,4-Diamino-N10-methylpteroic acid, 4-Amino-4-deoxy-10-methylpteroic acid, 4-Amino-4-deoxy-N10-methylpteroic acid, 4-Deoxy-4-amino-N10-methylpteroic acid, 4-[N-[(2,4-Diaminopyrimido[4,5-b]pyrazin-6-yl)methyl]-N-methylamino]benzoic acid, NSC 131463, NSC 133723, p-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoic acid, 4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoic Acid, 4-Amino-N10-methylpteroic Acid, APA, 4-Amino-4-deoxy-N10-methylpteroic acid, 4-(N-(2,4-diamino-6-pteridinyl-*methyl)-N-methyl-, 4-(N-(2,4-diamino-6-pteridinylmethyl)*-N-methyl-, Bis(4-((2,4-Diaminopteridin-6-Ylmethyl)Methylamino)Benzoic) Acid Hydrochloride Tetrahydrate, 4-[N-(2,4-Diamino-6-pteridinylmethyl)-N-methylamino]benzoic acid hemihydrochloride dihydrate, 4-{[(2,4-Diaminopteridin-6-Yl)Methyl](Methyl)Amino}Benzoic Acid

Description

Impurity Methotrexate EP Impurity E
Stability Hygroscopic
Applications DAMPA is a Methotrexate (M260675) analog (1). DAMPA is an antitumor agent (2).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Martinelli, J. et al.: J. Med. Chem. 1979 Jul;22(7):869-742. Oudart, J. et al.: Ann Biol Clin (Paris). 2016 Jun 1;74(3):333-7

• Brand: TRC

Chemical properties

• Molecular weight: 325.33
• Formula: C₁₅H₁₅N₇O₂
• Color/Form: Dark Yellow To Dark Brown
• InChI: InChI=1S/C15H15N7O2/c1-22(10-4-2-8(3-5-10)14(23)24)7-9-6-18-13-11(19-9)12(16)20-15(17)21-13/h2-6H,7H2,1H3,(H,23,24)(H4,16,17,18,20,21)
• InChI key: InChIKey=LWCXZSDKANNOAR-UHFFFAOYSA-N
• SMILES: CN(Cc1cnc2nc(=N)[nH]c(N)c2n1)c1ccc(C(=O)O)cc1