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Daprodustat Bishydroxylated Metabolite

CAS:

Ref. TR-D193370

Daprodustat Bishydroxylated Metabolite
TRC

    Product Information

    Name:Daprodustat Bishydroxylated Metabolite
    Controlled Product
    Synonyms:
    • GSK2391220A
    • 2-(6-Hydroxy-1,3-bis((1r,4R)-4-hydroxycyclohexyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamido)acetic acid
    Brand:TRC
    Description:

    Impurity Daprodustat Bishydroxylated Metabolite
    Applications Daprodustat Metabolite is a metabolite of Daprodustat (D193368). Daprodustat is a novel HIF (Hypoxia inducible factor)-prolyl hydroxylase inhibitor.
    References Olson, E., et al.: Vasc. Med., 19, 473 (2014);

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    Chemical properties

    Molecular weight:425.43
    Formula:C19H27N3O8
    Color/Form:Neat
    InChI:InChI=1S/C19H27N3O8/c23-12-5-1-10(2-6-12)21-17(28)15(16(27)20-9-14(25)26)18(29)22(19(21)30)11-3-7-13(24)8-4-11/h10-13,23-24,28H,1-9H2,(H,20,27)(H,25,26)
    InChI key:InChIKey=TVKUESBHMRAOSV-NGBBIHDVSA-N
    SMILES:O=C(O)CNC(=O)c1c(O)n([C@H]2CC[C@H](O)CC2)c(=O)n([C@H]2CC[C@H](O)CC2)c1=O

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