Product Information
Name:Darinaparsin
Controlled Product
Synonyms:
- N-[S-(Dimethylarsino)-N-L-γ-glutamyl-L-cysteinyl]-glycine
- Dimethylarsinic Glutathione
- ZIO 101
- Zinapar
- L-γ-Glutamyl-S-(dimethylarsino)-L-cysteinyl-glycine
Brand:TRC
Description:Applications Darinaparsin is an arsenic cytotoxin that has been used in pharmacological activities to evaluate the effect on survival an radiosensitivity of tumor cells in vitro under normoxia and hypoxia and in vivo using xenograft models. Darinaparsin has significant and preferential cytotoxic and radiosensitizing effects on solid tumors as compared with normal cells. Darinaparsin may therefore increase the therapeutic index of radiation therapy and has near term translational potential. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Tian, J., et al.: Clin. Cancer Res., 18, 3366 (2012); Ning, S., et al.: Int. J. Radiat. Oncol. Biol. Phys., 65, 493 (2006);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:411.31
Formula:C12H22AsN3O6S
Color/Form:Neat
InChI:InChI=1S/C12H22AsN3O6S/c1-13(2)23-6-8(11(20)15-5-10(18)19)16-9(17)4-3-7(14)12(21)22/h7-8H,3-6,14H2,1-2H3,(H,15,20)(H,16,17)(H,18,19)(H,21,22)/t7-,8-/m0/s1
InChI key:InChIKey=SGFJJNBUMXQSMU-PDBXOOCHSA-N
SMILES:CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)OCC1CO1
Technical inquiry about: Darinaparsin
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