4,4'-Dichlorodiphenyldichloroethylene - d8

CAS: 93952-19-3

Ref. TR-D195207

Product Information

• Name: 4,4'-Dichlorodiphenyldichloroethylene - d8
• Synonyms: Benzene-1,2,4,5-d4, 3,3'-(dichloroethenylidene)bis[6-chloro- (9CI), 4,4'-DDE D8, 1,1-Dichloro-2,2-Bis(4-Chlorophenyl-D4)Ethylene, 4,4’-Dde D8, P,P’-Dde-D4, P,P’-Dde D8

Description

Applications 4,4'-DDE - d8 is a metabolite of DDT - d8 (D434197), a synthetic organochlorine insecticide that functions by opening sodium ion channels in the insects’ neurons, causing them to fire spontaneously which in turn leads to death. 4,4'-DDE - d8 has shown to have endocrine disrupting effects on gonadotropin hormones in pituitary gonadotrope cells.
References Saschenbrecker, P.W.: Can. J. Comp. Med., 37, 203 (1973); Balkew, M. et al.: Paras. Vect., 3, No pp. given (2010); Kikankie, C.K. et al.: Malaria J., 9, No pp. given. (2010); Battu, R.S. et al.: Sci. Total Environ., 78, 173 (1989); Zhou, J., et. al.: Environ. Toxicol. Phar., 37, 1194 (2014)

• Brand: TRC

Chemical properties

• Molecular weight: 326.07
• Formula: C₁₄H₈Cl₄
• Color/Form: White Solid
• InChI: InChI=1S/C14H8Cl4/c15-11-5-1-9(2-6-11)13(14(17)18)10-3-7-12(16)8-4-10/h1-8H/i1D,2D,3D,4D,5D,6D,7D,8D
• InChI key: InChIKey=UCNVFOCBFJOQAL-PGRXLJNUSA-N
• SMILES: [2H]c1c([2H])c(C(=C(Cl)Cl)c2c([2H])c([2H])c(Cl)c([2H])c2[2H])c([2H])c([2H])c1Cl