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N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine-d3
CAS:
Ref. TR-D199037
5mg
3,199.00€
500µg
461.00€
2500µg
1,798.00€
Product Information
Name:N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine-d3
Controlled Product
Synonyms:
- S-Me-DM1-d3
Brand:TRC
Description:Applications Isotope labelled N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine is an active metabolite of Maytansine (M197940), inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer.References Remillard, S., et. al.: Science, 189, 1002 (1975); Prota, A.E., et. al.: P. Natl. Acad. Sci. USA, 111, 13817 (2014)
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Chemical properties
Molecular weight:755.33
Formula:C36H47D3ClN3O10S
Color/Form:Neat
InChI:InChI=1S/C36H50ClN3O10S/c1-20-11-10-12-27(47-8)36(45)19-26(48-34(44)38-36)21(2)32-35(4,50-32)28(49-33(43)22(3)39(5)29(41)13-14-51-9)18-30(42)40(6)24-16-23(15-20)17-25(46-7)31(24)37/h10-12,16-17,21-22,26-28,32,45H,13-15,18-19H2,1-9H3,(H,38,44)/b12-10+,20-11+/t21-,22+,26+,27-,28+,32+,35+,36+/m1/s1/i8D3
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