Debromo Chloro Nicergoline

CAS: 38536-28-6

Ref. TR-D208800

Product Information

• Name: Debromo Chloro Nicergoline
• Synonyms: [(6aR,9R,10aS)-10a-Methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]methyl 5-Chloropyridine-3-carboxylate, Nicergoline Imp. A (EP), Chloronicergoline, Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-[5-chloro-3-pyridinecarboxylate], Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 5-chloro-3-pyridinecarboxylate (ester), (8β)- (9CI), [(8β)-10-Methoxy-1,6-dimethylergolin-8-yl]methyl 5-chloro-3-pyridinecarboxylate
• Brand: TRC

Description

Impurity Nicergoline EP Impurity A
Applications Debromo Chloro Nicergoline is an impurity of Nicergoline (N394550). Nicergoline is a drug used for age-dependent cognitive impairment and it protects cultured neurons against β-amyloid toxicity.
References Mizuno, T., et. al.: Brain Res., 1066, 78 (2005)

Chemical properties

• Molecular weight: 439.93
• Formula: C₂₄H₂₆ClN₃O₃
• Color/Form: Neat
• InChI: InChI=1S/C24H26ClN3O3/c1-27-13-17-8-21-24(30-3,19-5-4-6-20(27)22(17)19)9-15(12-28(21)2)14-31-23(29)16-7-18(25)11-26-10-16/h4-7,10-11,13,15,21H,8-9,12,14H2,1-3H3/t15-,21-,24+/m1/s1
• InChI key: InChIKey=DIRAHWOBGZRAEU-FVFQAYNVSA-N
• SMILES: CO[C@]12C[C@@H](COC(=O)c3cncc(Cl)c3)CN(C)[C@@H]1Cc1cn(C)c3cccc2c13