1,2-Dihydrobudesonide (Mixture of diastereomers)

CAS: 137174-25-5

Ref. TR-D229330

Product Information

• Name: 1,2-Dihydrobudesonide (Mixture of diastereomers)
• Synonyms: 16alpha,17-[(1RS)-Butylidenebis(oxy)]-11beta,21-dihydroxypregn-4-ene-3,20-dione, (11beta,16alpha)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxy-pregn-4-ene-3,20-dione, 1,2-Dihydrobudesonide,Budesonide Imp. G (EP)
• Brand: TRC
• Description: Impurity Budesonide EP Impurity GApplications 1,2-Dehydrobudesonide (Budesonide EP Impurity G) is an impurity in the synthesis of Budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Clissold, S.P., et al.: Drugs, 28, 485 (1984),

Chemical properties

• Molecular weight: 432.55
• Formula: C₂₅H₃₆O₆
• Color/Form: Neat
• InChI: InChI=1S/C25H36O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h10,16-18,20-22,26,28H,4-9,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1
• InChI key: InChIKey=UEXJIOHTZFZGOQ-PZETWVICSA-N
• SMILES: CCCC1OC2C[C@H]3[C@@H]4CCC5=CC(=O)CC[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)C2(C(=O)CO)O1