Estimated delivery in United States, on Friday 27 Dec 2024
Product Information
Name:
Delamanid
Synonyms:
- Imidazo[2,1-b]oxazole
- 2,3-dihydro-2-methyl-6-nitro-2-[[4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl]phenoxy]methyl]-
- (2R)-
- (2R)-2,3-Dihydro-2-methyl-6-nitro-2-[[4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl]phenoxy]methyl]imidazo[2,1-b]oxazole
- OPC 67683
- Deltyba
- Imidazo[2,1-b]oxazole, 2,3-dihydro-2-methyl-6-nitro-2-[[4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl]phenoxy]methyl]-, (2R)-
- Opc 67683
- Unii-8Oot6M1Pc7
Description:
Stability Hygroscopic
Applications Delamanid is a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in vitro and in vivo activity against drug-resistant strains of Mycobacterium tuberculosis.
References Gler, M.T., et al.: New Engl. J. Med., 366, 2151 (2012); Skripconoka, V., et al.: Eur. Respir. J., 41, 1393 (2012); Diacon, A.H., et al.: Int. J. Tuberc. Lung D., 15, 949 (2011); Zhang, Q., et al.: Cell Biochem. Biophys., 67, 957 (2013)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
534.48
Formula:
C25H25F3N4O6
Color/Form:
Neat
InChI:
InChI=1S/C25H25F3N4O6/c1-24(15-31-14-22(32(33)34)29-23(31)38-24)16-35-18-4-2-17(3-5-18)30-12-10-20(11-13-30)36-19-6-8-21(9-7-19)37-25(26,27)28/h2-9,14,20H,10-13,15-16H2,1H3/t24-/m1/s1
SMILES:
C[C@]1(COc2ccc(N3CCC(Oc4ccc(OC(F)(F)F)cc4)CC3)cc2)Cn2cc([N+](=O)[O-])nc2O1
MDL:
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Technical inquiry about: TR-D230660 Delamanid
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