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Delanzomib

CAS:

Ref. TR-D230710

50mg
1,443.00€
Delanzomib
TRC

Product Information

Name:Delanzomib
Controlled Product
Synonyms:
  • [(1R)-1-[[(2S,3R)-3-Hydroxy-1-oxo-2-[[(6-phenyl-2-pyridinyl)carbonyl]amino]butyl]amino]-3-methylbutyl]boronic Acid
  • CEP 18770
  • CIP 18770
  • CT 47098
  • NPH 007098
  • [(1R)-1-[[(2S,3R)-3-Hydroxy-2-[[(6-phenylpyridin-2-yl)carbonyl]amino]-1-oxobutyl]amino]-3-methylbutyl]boronic Acid
Brand:TRC
Description:Stability HygroscopicApplications Delanzomib is an orally active proteasome inhibitor. Delanzomib has been shown to down-modulate NF-κB, induce apoptosis, inhibit angiogenesis and M-CSF-RANKL-induced osteoclastogenesis.References Piva, R. et al.: Blood, 111, 2765 (2008); Sanchez, E. et al.: Br. J. Haematol., 148, 569 (2010);
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:413.28
Formula:C21H28BN3O5
Color/Form:Neat
InChI:InChI=1S/C21H28BN3O5/c1-13(2)12-18(22(29)30)24-21(28)19(14(3)26)25-20(27)17-11-7-10-16(23-17)15-8-5-4-6-9-15/h4-11,13-14,18-19,26,29-30H,12H2,1-3H3,(H,24,28)(H,25,27)/t14-,18+,19+/m1/s1
InChI key:InChIKey=SJFBTAPEPRWNKH-CCKFTAQKSA-N
SMILES:CC(C)C[C@H](NC(=O)[C@@H](NC(=O)c1cccc(-c2ccccc2)n1)[C@@H](C)O)B(O)O

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