N-Demethyl-3-methoxy-4-hydroxytamoxifen Hydrochloride (E,Z mixture)
CAS:
Ref. TR-D231060
25mg
1,964.00€
2500µg
304.00€
Product Information
Name:N-Demethyl-3-methoxy-4-hydroxytamoxifen Hydrochloride (E,Z mixture)
Controlled Product
Synonyms:
- 2-methoxy-4-[(E)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol;hydrochloride
Brand:TRC
Description:Applications N-Demethyl-3-methoxy-4-hydroxytamoxifen is an metabolite of Tamoxifen (T006000), a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor.References Zhang, F., et al.: Chem. Rs. Toxicol., 13, 53 (2000); Sutherland, R., et al.: Nature, 267, 434 (1977); Lerner, L., et al.: Cancer Res., 50, 4177 (1990); Love, R., et al.: J. Clin. Oncol., 20 2559 (2002)
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Chemical properties
Molecular weight:439.97
Formula:C26H30ClNO3
Color/Form:Neat
InChI:InChI=1S/C26H29NO3.ClH/c1-4-23(19-8-6-5-7-9-19)26(21-12-15-24(28)25(18-21)29-3)20-10-13-22(14-11-20)30-17-16-27-2;/h5-15,18,27-28H,4,16-17H2,1-3H3;1H/b26-23+;
InChI key:InChIKey=WZCYQXAQEQRARN-VQSOISJUSA-N
SMILES:CC/C(=C(/c1ccc(OCCNC)cc1)c1ccc(O)c(OC)c1)c1ccccc1.Cl
Technical inquiry about: N-Demethyl-3-methoxy-4-hydroxytamoxifen Hydrochloride (E,Z mixture)
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