![N-De[2-(methylsulfonyl)ethyl] Lapatinib](https://static.cymitquimica.com/products/TR/img/D231270.png "Click to enlarge")
Estimated delivery in United States, on Tuesday 14 Jan 2025
Product Information
Name:
N-De[2-(methylsulfonyl)ethyl] Lapatinib
Controlled Product
Synonyms:
- 6-[5-(Aminomethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-4-quinazolinamine
- [6-(5-Aminomethylfuran-2-yl)quinazolin-4-yl][3-chloro- 4-(3-fluorobenzyloxy)phenyl]amine
Description:
Applications A reactive metabolite of Lapatinib (L175800) which is associated with various drug toxicities. Lapatinib is metabolized mainly by P450 3A4 to form O- and N-dealkylated metabolites.
References He, K., et al.: Chem. Res. Toxicol., 11, 252 (1998), Rusnuk, D., et al.: Cancer Res., 61, 7196 (2001), Li, X., et al.: Drug Metab. Dispos., 37, 1242 (2009),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
474.91
Formula:
C26H20ClFN4O2
Color/Form:
Neat
InChI:
InChI=1S/C11H11N5/c1-6-5-13-7-3-4-8-10(9(7)14-6)15-11(12)16(8)2/h3-5H,1-2H3,(H2,12,15)
InChI key:
InChIKey=DVCCCQNKIYNAKB-UHFFFAOYSA-N
SMILES:
Cc1cnc2ccc3c(nc(N)n3C)c2n1
MDL:
Melting point:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-D231270 N-De[2-(methylsulfonyl)ethyl] Lapatinib
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