6-Dehydro-21-deoxy Cortisol

CAS: 95815-40-0

Ref. TR-D231760

Product Information

• Name: 6-Dehydro-21-deoxy Cortisol
• Synonyms: (8S,9S,10R,11S,14S,17S)-17-acetyl-11,17-dihydroxy-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one

Description

Applications 6-Dehydro-21-deoxy Cortisol is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
References Hechter, O., et al.: Arch. Biochem. Biophys., 25, 457 (1950); Colingsworth, D.R., et al.: J. Biol. Chem., 203, 807 (1953); Florey, K., et al.: Anal. Profiles Drug Subs., 12, 277 (1983);

• Brand: TRC

Chemical properties

• Molecular weight: 344.445
• Formula: C₂₁H₂₈O₄
• Color/Form: Neat
• InChI: InChI=1S/C21H28O4/c1-12(22)21(25)9-7-16-15-5-4-13-10-14(23)6-8-19(13,2)18(15)17(24)11-20(16,21)3/h4-5,10,15-18,24-25H,6-9,11H2,1-3H3/t15-,16-,17-,18+,19-,20?,21+/m0/s1
• InChI key: InChIKey=OAHLBJQRWHQCCJ-IUWOMPCOSA-N
• SMILES: CC(=O)[C@]1(O)CC[C@H]2[C@@H]3C=CC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)CC21C