Deoxymannojirimycin Hydrochloride

CAS: 73465-43-7

Ref. TR-D240000

Product Information

• Name: Deoxymannojirimycin Hydrochloride
• Synonyms: (2R,3R,4R,5R)-2-(hydroxymethyl)piperidine-3,4,5-triol;hydrochloride

Description

Applications Deoxymannojirimycin has been shown to be a potent inhibitor of the mammalian Golgi alpha- mannosidase 1 activity, blocking the conversion of high-mannose oligosaccharides to complex-type oligosaccharides. However, it does not inhibit the biosynthesis of lipid- linked oligosaccharides.
References Eur. J. Biochem., 150, 41-46 (1985), J. Biol. Chem., 261, 4766 (1986), Seftor, R.E.B., et al.: Melanoma Res., 1, 43 (1991), Suzuki, S.S., et al.: J. Cell. Biochem., 51, 181 (1993)

• Brand: TRC

Chemical properties

• Molecular weight: 199.63
• Formula: C₆H₁₃NO₄·ClH
• Color/Form: Neat
• InChI: InChI=1S/C6H13NO4.ClH/c8-2-3-5(10)6(11)4(9)1-7-3;/h3-11H,1-2H2;1H/t3-,4-,5-,6-;/m1./s1
• InChI key: InChIKey=ZJIHMALTJRDNQI-MVNLRXSJSA-N
• SMILES: Cl.OC[C@H]1NC[C@@H](O)[C@@H](O)[C@@H]1O