Deoxysotalol

CAS: 16974-42-8

Ref. TR-D245550

Product Information

• Name: Deoxysotalol
• Synonyms: Sotalol Impurity A, Methanesulfonamide, N-(4-(2-((1-methylethyl)amino)ethyl)phenyl)-, N-{4-[2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide

Description

Applications Deoxysotalol is the metabolite of Sotalol (S677300), a potent α-adrenergic receptor antagonist and A class III antiarrythmic. Several studies have examined deoxysotalol on its effects on prostaglandin (PGF2a and 15-methyl PGF2α)-evoked contraction using isolated rat uterus and also in potentiating the contractile effects of Oxytocin (O878500).
References Uloth, et al.: J. Med. Chem., 9, 88 (1966); Narendranath, K.A., et al.: Euro. J. Pharmacol., 46, 15 (1977); Gautam, C.S., et al., Indian. J. Med. Rsch., 76, 107 (1982);

• Brand: TRC

Chemical properties

• Molecular weight: 256.36
• Formula: C₁₂H₂₀N₂O₂S
• Color/Form: Off White
• InChI: InChI=1S/C12H20N2O2S/c1-10(2)13-9-8-11-4-6-12(7-5-11)14-17(3,15)16/h4-7,10,13-14H,8-9H2,1-3H3
• InChI key: InChIKey=ZCMDXDQUYIWEKB-UHFFFAOYSA-N
• SMILES: c1ccc(CCN2CCC(Nc3ccccc3)CC2)cc1