1-[2-Deoxy-3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-b-D-erythro-pentofuranosyl]-1H-1,2,4-triazole-3-carboxamide

CAS: 359861-06-6

Ref. TR-D278780

Product Information

• Name: 1-[2-Deoxy-3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-b-D-erythro-pentofuranosyl]-1H-1,2,4-triazole-3-carboxamide
• Synonyms: 1-[(6aR,8R)-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-1,2,4-triazole-3-carboxamide
• Brand: TRC
• Description: Applications 1-[2-Deoxy-3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-β-D-erythro-pentofuranosyl]-1H-1,2,4-triazole-3-carboxamide is an intermediate in the synthesis of 2’-Deoxyribavirin-5’-triphosphate (D2149940) Triethylamine Salt, a potential new inhibitor for HIV-1 replication.References Vivet-Boudou, V., et al.: Nucleos. Nucleot. Nucl., 26, 743 (2007)

Chemical properties

• Molecular weight: 470.71
• Formula: C₂₀H₃₈N₄O₅Si₂
• Color/Form: Neat
• InChI: InChI=1S/C20H38N4O5Si2/c1-12(2)30(13(3)4)26-10-17-16(28-31(29-30,14(5)6)15(7)8)9-18(27-17)24-11-22-20(23-24)19(21)25/h11-18H,9-10H2,1-8H3,(H2,21,25)/t16?,17-,18-/m1/s1
• InChI key: InChIKey=BROATPLWSARHCT-UKKPGEIXSA-N
• SMILES: CC(C)[Si]1(C(C)C)OC[C@H]2O[C@@H](n3cnc(C(N)=O)n3)CC2O[Si](C(C)C)(C(C)C)O1