Product Information
Name:2'-Deoxy-6-thio Guanosine
Controlled Product
Synonyms:
- 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purine-6-thione
Brand:TRC
Description:Applications Guanosine (G837900) derivative with cancer chemotherapeutic properties. It is involved in the inhibition of human RNase H-mediated RNA cleavage from DNA-RNA duplexes via incorporation into DNA.References Momparler, R.L. et al.: Cancer Treat. Rep., 62, 135 (1978); Krynetskaia, N.F. et al.: Mol. Pharmacol., 56, 841 (1999);
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Chemical properties
Molecular weight:283.31
Formula:C10H13N5O3S
Color/Form:Neat
InChI:InChI=1S/C10H13N5O3S/c11-10-13-8-7(9(19)14-10)12-3-15(8)6-1-4(17)5(2-16)18-6/h3-6,16-17H,1-2H2,(H3,11,13,14,19)/t4-,5+,6+/m0/s1
InChI key:InChIKey=SCVJRXQHFJXZFZ-KVQBGUIXSA-N
SMILES:Nc1nc(=S)c2ncn([C@H]3C[C@H](O)[C@@H](CO)O3)c2[nH]1
Technical inquiry about: 2'-Deoxy-6-thio Guanosine
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