Deracoxib

CAS: 169590-41-4

Ref. TR-D281920

Product Information

• Name: Deracoxib
• Synonyms: 4-[3-(Difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl]-benzenesulfonamide, 4-[3-(Difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl]benzenesulfonamide, 4-[5-(3-Fluoro-4-methoxyphenyl)-3-(difluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide, Deram, Deramaxx, SC 046, SC 46, SC 59046, 4-[3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl]benzenesulfonamide, Benzenesulfonamide, 4-3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl-, Sc 046, Sc 46, Sc 59046

Description

Applications Deracoxib is a non-steroidal anti-inflammatory drug (NSAID) of the coxib class. Deracoxin is a selective cyclooxygenase-2 (COX-2) inhibitor used in the treatment of osteoarthritis in dogs. At low doses, adminsitartion of Deracoxin showed no factors associated with gastrointestinal tract perforation.
References Lascelles, B.D.X. et al.: J. Am. Vet. Med. Assoc., 227, 1112 (2005); Anderson, G.D. et al.: Inflam. Res., 58, 109 (2009); Brainard, B.M. et al.: Am. J. Vet. Res., 68, 251 (2007);

• Brand: TRC

Chemical properties

• Molecular weight: 397.37
• Formula: C₁₇H₁₄F₃N₃O₃S
• Color/Form: Light Brown
• InChI: InChI=1S/C17H14F3N3O3S/c1-26-16-7-2-10(8-13(16)18)15-9-14(17(19)20)22-23(15)11-3-5-12(6-4-11)27(21,24)25/h2-9,17H,1H3,(H2,21,24,25)
• InChI key: InChIKey=WAZQAZKAZLXFMK-UHFFFAOYSA-N
• SMILES: COc1ccc(-c2cc(C(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1F