4-Desacetyl Vincristine Methosulfate

CAS: 3704-01-6

Ref. TR-D288729

Product Information

• Name: 4-Desacetyl Vincristine Methosulfate
• Synonyms: Vincaleukoblastine, O4-deacetyl-22-oxo-, Leurocristine, 4-deacetyl- (8CI), Leurocristine, deacetyl- (7CI), 2H-3,7-Methanoazacycloundecino[5,4-b]indole, vincaleukoblastine deriv., O4-Deacetyl-22-oxovincaleukoblastine, 4-Deacetylvincristine, 4-Desacetylvincristine
• Brand: TRC
• Description: Applications A metabolite of Vincristine in bile. Antitumor agent used against human colon carcinoma.References Houghton, J.A., et al.: Anal. Biochem., 134, 450 (1983), Sethi, V.S., et al.: Cancer Res., 45, 5386 (1985), Horton, J.K., et al.: Biochem. Pharmacol., 38, 1727 (1989),

Chemical properties

• Molecular weight: 782.92
• Formula: C₄₄H₅₄N₄O₉
• Color/Form: Neat
• InChI: InChI=1S/C44H54N4O9/c1-6-40(53)21-26-22-43(38(51)56-4,34-28(13-17-46(23-26)24-40)27-11-8-9-12-31(27)45-34)30-19-29-32(20-33(30)55-3)48(25-49)36-42(29)15-18-47-16-10-14-41(7-2,35(42)47)37(50)44(36,54)39(52)57-5/h8-12,14,19-20,25-26,35-37,45,50,53-54H,6-7,13,15-18,21-24H2,1-5H3/t26-,35-,36+,37+,40-,41+,42+,43-,44-/m0/s1
• InChI key: InChIKey=KLIAZUVLFVLIOU-XWUVELSPSA-N
• SMILES: CC[C@]1(O)C[C@H]2C[N@@](CCc3c([nH]c4ccccc34)[C@@](C(=O)OC)(c3cc4c(cc3OC)N(C=O)[C@H]3C(O)(C(=O)OC)[C@H](O)[C@@]5(CC)C=CCN6CC[C@@]43[C@@H]65)C2)C1.COS(=O)(=O)O