Desethyl Chloroquine

CAS: 1476-52-4

Ref. TR-D288735

Product Information

• Name: Desethyl Chloroquine
• Synonyms: N4-(7-Chloro-4-quinolinyl)-N1-ethyl-1,4-pentanediamine, Deethylchloroquine, Monodeethylchloroquine, NSC 13254, WR 29623, Desethyl Cloroquine, (±)-Desethylchloroquine, 1,4-Pentanediamine N4-(7-chloro-4-quinolinyl)-N1-ethyl-, 1,4-Pentanediamine, N⁴-(7-chloro-4-quinolinyl)-N¹-ethyl-, 4-[[1-Methyl-4-((ethylamino)butyl]amino)]-7-chloroquinoline, 7-Chloro-4-(4-N-ethylamino-1-methylbutylamino)quinoline, Chloroquine, deethyl-, Monodesethylchloroquine, N-Deethylchloroquine, N⁴-(7-Chloro-4-quinolinyl)-N¹-ethyl-1,4-pentanediamine, Nsc 13254, N~4~-(7-chloroquinolin-4-yl)-N~1~-ethylpentane-1,4-diamine, Quinoline, 7-chloro-4-[[4-(ethylamino)-1-methylbutyl]amino]-, Wr 29623

Description

Applications Desethyl Chloroquine is the major product of the stereoselective human metabolism of Chloroquine, used for the therapy and prevention of malaria. It is a COVID19-related research product.
References Essien, E., et al.: J. Pharm. Pharmacol., 38, 543 (1986), Akintonwa, A., et al.: Ther. Drug Monit., 10, 147 (1988), Boelaert, J., et al.: AIDS, 15, 2205 (2001), Basco, L., et al.: Antimicrob. Agents Chemother., 47, 1391 (2003),

• Brand: TRC

Chemical properties

• Molecular weight: 291.82
• Formula: C₁₆H₂₂ClN₃
• Color/Form: Light Yellow To Dark Yellow
• InChI: InChI=1S/C16H22ClN3/c1-3-18-9-4-5-12(2)20-15-8-10-19-16-11-13(17)6-7-14(15)16/h6-8,10-12,18H,3-5,9H2,1-2H3,(H,19,20)
• InChI key: InChIKey=MCYUUUTUAAGOOT-UHFFFAOYSA-N
• SMILES: CCNCCCC(C)Nc1ccnc2cc(Cl)ccc12