N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine-d4 Dihydrochloride

CAS: 111974-74-4

Ref. TR-D288743

Product Information

• Name: N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine-d4 Dihydrochloride
• Synonyms: 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine-d4 Dihydrochloride, DBTP-d4, 11-(1-Piperazinyl)-Dibenzo[B,F][1,4]Thiazepine Dihydrochloride, 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine,2HCl, 11-(Piperazin-1-Yl)Dibenzo[B,F][1,4]Thiazepine, 11-Piperazin-1-Yldibenzo[B,F][1,4]Thiazepine Dihydrochloride, 11-Piperazin-1-yl-dibenzo[b,f][1,4]thiazepine dihydrochloride, 11-Piperazine-Dibenzo[B,F][1,4]Thiazepine Hydrochloride, 11-Piperazinodibenzo[b,f][1,4]thiazepine dihydrochloride, 11-Piperazynil-Dibenzo[B,F][1,4]Thiazepine Dihydrochloride, 11-piperazinyl-dibenzo[b,f][1,4]thiazepine 2HCl, Dbtp, DibenzoB,F1,4Thiazepine-11-Piperazine2Hcl, Dibenzo[b,f][1,4]thiazepine, 11-(1-piperazinyl)-, dihydrochloride, Dibenzo[b,f][1,4]thiazepine, 11-(1-piperazinyl)-, hydrochloride (1:2), dibenzo[b,f][1,4]thiazepine-11-[10H]piperazine dihydrochloride

Description

Applications A labelled metabolite of Quetiapine (Q510000), a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic.
References DeVane, C., et al.: Clin. Pharmacokinet., 40, 509 (2001), Lin, S., et al.: J. Anal. Toxicol., 28, 443 (2004), Zhou, S., et al.: Curr. Drug Metab., 5, 415 (2004), Grimm, S., et al.: Br. J. Clin. Pharmacol., 61, 58 (2006),

• Brand: TRC

Chemical properties

• Molecular weight: 299.427
• Formula: C₁₇H₁₅D₄Cl₂N₃S
• Color/Form: Neat
• InChI: InChI=1S/C17H17N3S.2ClH/c1-3-7-15-13(5-1)17(20-11-9-18-10-12-20)19-14-6-2-4-8-16(14)21-15;;/h1-8,18H,9-12H2;2*1H/i9D2,10D2
• InChI key: InChIKey=JLOAJISUHPIQOX-YQUBHJMPSA-N
• SMILES: [2H]C1([2H])CN(C2=Nc3ccccc3Sc3ccccc32)CC([2H])([2H])N1