3-Desethyl-3-(2-phthalimidoethyl) Phthaloyl Amlodipine

Ref. TR-D289510

Product Information

• Name: 3-Desethyl-3-(2-phthalimidoethyl) Phthaloyl Amlodipine
• Synonyms: 3-O-[2-(1,3-dioxoisoindol-2-yl)ethyl] 5-O-methyl 4-(2-chlorophenyl)-2-[2-(1,3-dioxoisoindol-2-yl)ethoxymethyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
• Brand: TRC
• Description: Stability Light and Temperature SensitiveApplications 3-Desethyl-3-(2-phthalimidoethyl) Phthaloyl Amlodipine is a derivative of Amlodipine (A633495); a dihydropyridine calcium channel blocker where activity mainly resides in the (-)-isomer.References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987); Haria, M., et al.: Drugs, 50, 560 (1995)

Chemical properties

• Molecular weight: 684.091
• Formula: C₃₆H₃₀ClN₃O₉
• Color/Form: Neat
• InChI: InChI=1S/C36H30ClN3O9/c1-20-28(35(45)47-2)29(25-13-7-8-14-26(25)37)30(36(46)49-18-16-40-33(43)23-11-5-6-12-24(23)34(40)44)27(38-20)19-48-17-15-39-31(41)21-9-3-4-10-22(21)32(39)42/h3-14,29,38H,15-19H2,1-2H3
• InChI key: InChIKey=IXCREHNCTAMHPL-UHFFFAOYSA-N
• SMILES: COC(=O)C1=C(C)NC(COCCN2C(=O)c3ccccc3C2=O)=C(C(=O)OCCN2C(=O)c3ccccc3C2=O)C1c1ccccc1Cl