N-Demethylclindamycin

CAS: 22431-45-4

Ref. TR-D291495

Product Information

• Name: N-Demethylclindamycin
• Synonyms: L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio- (9CI), L-threo-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, trans- α- (8CI), L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, (2S-trans)-, (7S)-7-Chloro-7-deoxy-1'-demethyllincomycin, 1'-Demethylclindamycin, 7-Chloro-N-demethyllincomycin
• Brand: TRC
• Description: Applications N-Demethylclindamycin is an impurity of Clindamycin (C580000, HCl salt) which is a semi-synthetic antibiotic prepared from Lincomycin.References Birkenmeyer, R.D., et al.: J. Med. Chem., 13, 616 (1970), Oesterling, et al.: J. Pharm. Sci., 59, 63 (1970), Gray, J.E., et al.: Toxicol. Appl. Pharmacol., 21, 516 (1972), Brown, L.W., et al.: Anal. Profiles Drug Subs., 10, 75 (1981),

Chemical properties

• Molecular weight: 410.96
• Formula: C₁₇H₃₁ClN₂O₅S
• Color/Form: Neat
• InChI: InChI=1S/C17H31ClN2O5S/c1-4-5-9-6-10(19-7-9)16(24)20-11(8(2)18)15-13(22)12(21)14(23)17(25-15)26-3/h8-15,17,19,21-23H,4-7H2,1-3H3,(H,20,24)/t8-,9+,10-,11+,12-,13+,14+,15+,17+/m0/s1
• InChI key: InChIKey=HDBHHHCDEYATPY-LLKZWYOWSA-N
• SMILES: CCC[C@@H]1CN[C@@H](C(=O)N[C@H]([C@H](C)Cl)[C@H]2O[C@H](SC)C(O)C(O)[C@H]2O)C1