2-Desmethylene-2-hydroxymethyl Ethacrynic Acid Potassium Salt

CAS: 95772-54-6

Ref. TR-D291795

Product Information

• Name: 2-Desmethylene-2-hydroxymethyl Ethacrynic Acid Potassium Salt
• Synonyms: 2-[2,3-Dichloro-4-[2-(hydroxymethyl)-1-oxobutyl]phenoxy]acetic Acid Potassium Salt
• Brand: TRC

Description

Applications 2-Desmethylene-2-hydroxymethyl Ethacrynic Acid is a degradation product of Ethacrynic Acid (E676000), a diuretic used to treat high blood pressure and swelling caused by congestive heart failure, liver failure and kidney failure.
References Yarwood, R. J., et. al.: J. Pharmaceut. Sci., 74, 220 (1985); Beyer, et al.: J. Pharmacol. Exp. Ther., 147, 1 (1965); Kim., et al.: Am. J. Cardiol., 27, 407 (1971); Williamson, H.E., et al.: J. Clin. Pharmacol., 17, 663 (1977)

Chemical properties

• Molecular weight: 359.24
• Formula: C₁₃H₁₃Cl₂KO₅
• Color/Form: Neat
• InChI: InChI=1S/C13H14Cl2O5.K/c1-2-7(5-16)13(19)8-3-4-9(12(15)11(8)14)20-6-10(17)18;/h3-4,7,16H,2,5-6H2,1H3,(H,17,18);/q;+1/p-1
• InChI key: InChIKey=JNGHKYIUBOITID-UHFFFAOYSA-M
• SMILES: CCC(CO)C(=O)c1ccc(OCC(=O)O[K])c(Cl)c1Cl