2-O-Desmethyl Cisapride

CAS: 102671-04-5

Ref. TR-D291985

Product Information

• Name: 2-O-Desmethyl Cisapride
• Synonyms: cis-4-Amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-hydroxy-benzamide, rel-4-Amino-5-chloro-N-[1-[(3R,4S)-3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-hydroxybenzamide, 2-O-Desmethyl Acenalin, 2-O-Desmethyl Alimix, 2-O-Desmethyl Cipril, 2-O-Desmethyl Coordinax, 2-O-Desmethyl Prepulsid, 2-O-Desmethyl Propulsid, 2-O-Desmethyl Propulsin
• Brand: TRC

Description

Applications Minor Cisapride (C496400) metabolite.
References Meuldermans, W., et al.; Drug Metab. Disposition, 16, 410 (1988), Lowry J., et al.; Clin. pharmacol. ther., 73, 209 (2003), Shao L., et al.: Bioorg. Med. Chem. Lett., 19, 5679 (2009),

Chemical properties

• Molecular weight: 451.92
• Formula: C₂₂H₂₇ClFN₃O₄
• Color/Form: Neat
• InChI: InChI=1S/C22H27ClFN3O4/c1-30-21-13-27(8-2-10-31-15-5-3-14(24)4-6-15)9-7-19(21)26-22(29)16-11-17(23)18(25)12-20(16)28/h3-6,11-12,19,21,28H,2,7-10,13,25H2,1H3,(H,26,29)/t19-,21+/m1/s1
• InChI key: InChIKey=WUYNAGSDZADZCE-CTNGQTDRSA-N
• SMILES: CO[C@H]1CN(CCCOc2ccc(F)cc2)CC[C@H]1NC(=O)c1cc(Cl)c(N)cc1O