N-Desmethyl Sildenafil

CAS: 139755-82-1

Ref. TR-D292200

Product Information

• Name: N-Desmethyl Sildenafil
• Synonyms: Desmethylsildenafil,7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-, Piperazine, 1-[[3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]- (9CI), 1H-Pyrazolo[4,3-d]pyrimidine, piperazine deriv., 5-[2-Ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-Ethoxy-5-(piperazin-1-ylsulfonyl)phenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, N-Demethylsildenafil, N-Desmethylsildenafil, N-[3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxybenzene-1-sulfonyl]piperazine, UK 103320, 1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]piperazine
• Brand: TRC
• Description: Applications A metabolite of Sildenafil (S435001), an orally active selective type 5 cGMP phosphodiesterase inhibitor.References Walker, D; Xenobiotica, 29, 297 (1999), Shim, H., et al.: J. Pharm. Biomed. Anal., 30, 527 (2002), Kim, J., et al.: J. Pharm. Biomed. Anal., 32, 317 (2003), Pelander, A., et al.: J. Anal. Toxicol., 27, 226 (2003),

Chemical properties

• Molecular weight: 460.55
• Formula: C₂₁H₂₈N₆O₄S
• Color/Form: White To Off-White
• InChI: InChI=1S/C21H28N6O4S/c1-4-6-16-18-19(26(3)25-16)21(28)24-20(23-18)15-13-14(7-8-17(15)31-5-2)32(29,30)27-11-9-22-10-12-27/h7-8,13,22H,4-6,9-12H2,1-3H3,(H,23,24,28)
• InChI key: InChIKey=UZTKBZXHEOVDRL-UHFFFAOYSA-N
• SMILES: CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCNCC4)ccc3OCC)nc12