2-Desmethyl 4-Methyl Prilocaine

CAS: 744961-76-0

Ref. TR-D292285

Product Information

• Name: 2-Desmethyl 4-Methyl Prilocaine
• Synonyms: 2-(Propylamino)-p-propionotoluidide, (RS)-N-(4-Methylphenyl)-2-(propylamino)propanamide, Prilocaine Related Compound B, Prilocaine Hydrochloride Impurity E, Prilocaine Impurity E

Description

Impurity Prilocaine USP Related Compound B
Applications 2-Desmethyl 4-Methyl Prilocaine is an impurity in the synthesis of Prilocaine (P725000), a local anesthetic of the amino amide type. Prilocaine is often used in dentistry. Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. Prilocaine USP Related Compound B.
References Caliaro, G., et al.: J. Pharm. Biomed. Anal., 26, 427 (2001), Ulmeanu, S., et al.: Pharm. Res., 20, 1317 (2003),

• Brand: TRC

Chemical properties

• Molecular weight: 220.31
• Formula: C₁₃H₂₀N₂O
• Color/Form: Neat
• InChI: InChI=1S/C13H20N2O/c1-4-9-14-11(3)13(16)15-12-7-5-10(2)6-8-12/h5-8,11,14H,4,9H2,1-3H3,(H,15,16)
• InChI key: InChIKey=RUQVJLDZKPZLIG-JBUKQTOJSA-N
• SMILES: CN(C)c1ccc([C@H]2C[C@]3(C)C(=O)CC[C@@H]3[C@@H]3CC[C@]4(O)CC5(CCC4=C32)OCCO5)cc1