2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-(2-Acetylhydrazinyl)-2-oxoacetamide) Raltegravir

CAS: 1391918-17-4

Ref. TR-D293110

Product Information

• Name: 2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-(2-Acetylhydrazinyl)-2-oxoacetamide) Raltegravir
• Synonyms: 2-​[[1-​[4-​[[[(4-​Fluorophenyl)​methyl]​amino]​carbonyl]​-​1,​6-​dihydro-​5-​hydroxy-​1-​methyl-​6-​oxo-​2-​pyrimidinyl]​-​1-​methylethyl]​amino]​-​2-​oxo-​Acetic Acid 2-​Acetylhydrazide
• Brand: TRC
• Description: Applications 2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-(2-Acetylhydrazinyl)-2-oxoacetamide) Raltegravir is an impurity of a potent human immunodeficiency virus (HIV) integrase inhibitor. A novel anti-AIDS drug.References Wade, K., et al.: J. Pharmacol. Biomed. Anal., 8, 401 (1990), Hazuda, D., et al.: Science, 287, 646 (2000), Williams, J., et al.: Drug Metab. Dispos., 32, 1201 (2004), Duckett, C., et al.: Xenobiotica, 36, 59 (2006), Miners, J., et al.: Biochem. Pharmacol., 71, 1531 (2006), Summa, V., et al.: J. Med. Chem., 49, 6646 (2006),

Chemical properties

• Molecular weight: 462.43
• Formula: C₂₀H₂₃FN₆O₆
• Color/Form: Off-White
• InChI: InChI=1S/C20H23FN6O6/c1-10(28)25-26-17(32)16(31)24-20(2,3)19-23-13(14(29)18(33)27(19)4)15(30)22-9-11-5-7-12(21)8-6-11/h5-8,29H,9H2,1-4H3,(H,22,30)(H,24,31)(H,25,28)(H,26,32)
• InChI key: InChIKey=KPEBFOGKEOSYOS-UHFFFAOYSA-N
• SMILES: CC(=O)NNC(=O)C(=O)NC(C)(C)c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C