(2S,3S,4S,5R)-6-(2-(Difluoromethoxy)acetoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid

Ref. TR-D293346

Product Information

• Name: (2S,3S,4S,5R)-6-(2-(Difluoromethoxy)acetoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid
• Synonyms: (2S,3S,4S,5R,6S)-6-[2-(difluoromethoxy)acetyl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid

Description

Applications (2S,3S,4S,5R)-6-(2-(Difluoromethoxy)acetoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid is metabolite of 2-(Difluoromethoxy)-acetaldehyde (D442365(M)). 2-(Difluoromethoxy)-acetaldehyde is a derivative of 2-(Difluoromethoxy)ethanol (D423695(M)), which is a useful reactant in the synthetic preparation of N-substituted alkoxyalkanamides as modulators of the integrated stress response pathway. The glucuronide that is attached to 2-(Difluoromethoxy)-acetaldehyde by the glycosidic bond.
References Atton, H., et al.: PCT Int. Appl. (2020), WO 2020216766 A1

• Brand: TRC

Chemical properties

• Molecular weight: 302.183
• Formula: C₉H₁₂F₂O₉
• Color/Form: Neat
• InChI: InChI=1S/C9H12F2O9/c10-9(11)18-1-2(12)19-8-5(15)3(13)4(14)6(20-8)7(16)17/h3-6,8-9,13-15H,1H2,(H,16,17)/t3-,4-,5+,6-,8+/m0/s1
• InChI key: InChIKey=ZOOWWMBTDIYKAI-UQGZVRACSA-N
• SMILES: O=C(COC(F)F)O[C@@H]1O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]1O