O-Desmorpholinopropyl-O-methyl-gefitinib

CAS: 153437-78-6

Ref. TR-D296840

Product Information

• Name: O-Desmorpholinopropyl-O-methyl-gefitinib
• Synonyms: N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine,4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-6,7-dimethoxy-, N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxy-4-quinazolinamine
• Brand: TRC
• Description: Applications O-Desmorpholinopropyl-O-methyl-gefitinib is a anilinoquinazoline derivative of which acts as an inhibitor of tyrosine kinases and found to be allosteric inhibitors of the enzyme frutose 1,6-bisphosphatase. It serves as a lead to further drug design.References Wright, S. W., Bioorganic & Medicinal Chemistry Letters, 11, 17-21, (2000)

Chemical properties

• Molecular weight: 333.74
• Formula: C₁₆H₁₃ClFN₃O₂
• Color/Form: White To Off-White
• InChI: InChI=1S/C16H13ClFN3O2/c1-22-14-6-10-13(7-15(14)23-2)19-8-20-16(10)21-9-3-4-12(18)11(17)5-9/h3-8H,1-2H3,(H,19,20,21)
• InChI key: InChIKey=VOPNWXZDJKCCRE-UHFFFAOYSA-N
• SMILES: COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OC