Desoxymetasone-D5 (Major)

CAS: 382-67-2

Ref. TR-D296972

Product Information

• Name: Desoxymetasone-D5 (Major)
• Synonyms: (11ß,16a)-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione-D5, 17-Deoxydexamethasone-D5, 9-Fluoro-16a-methyl-1-corticosterone-D5, Desoximetasone-D5, Stidex-D5, Topicort-D5, Topicorte-D5, Topisolon-D5, (11Beta,16Alpha)-9-Fluoro-11,21-Dihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione, (11β,16α)-9-Fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, (16Alpha)-9-Fluoro-11,21-Dihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione, (8Xi,10Xi,13Xi,14Xi,16Alpha,17Xi)-9-Fluoro-11,21-Dihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione, 17-Deoxydexamethasone, 17-Deoxymethansone, 17-Deoxymethasone, 17-Desoximethasone, 9-Fluoro-11-beta,21-dihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione, 9-Fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione, 9-Fluoro-16α-methyl-Δ1-corticosterone, 9-Fluoro-16α-methyl-Δ¹-corticosterone, 9α-Fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione, A 41-304, A 41304, Brn 2228097, Deoxymethasone, Desossimetasone, Desossimetasone [DCIT], Desoximetason, Desoximetasona, Desoximetasona [INN-Spanish], Desoximetasone [USAN:INN], Desoximetasonum, Desoximetasonum [INN-Latin], Desoximethasone, Desoxymetasone, Desoxymethasone, Esperson, Flubason, Hoe 304, Ibaril, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-, (11beta,16alpha)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-, (11β,16α)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,21-dihydroxy-16α-methyl-, R 2113, Stidex, Stiedex, Topicort, Topicort LP, Topicorte, Topisolon, Unii-4E07Gxb7Au

Description

Applications Desoxymetasone-D5 is a labelled analogue of Desoxymetasone (D296970). Desoxymetasone is a fluorinated corticosteroid that is structurally related to Dexamethasone (D298800), and is used as a topical cream to treat eczema.
References Heel, R., et al.: Drugs, 16, 302 (1978); Henry, M., et al.: Curr. Med. Res. Opin., 6, 502 (1980); Sehgal, Int. J. Derm., 15, 770 (1976)

• Brand: TRC

Chemical properties

• Molecular weight: 381.49
• Formula: C₂₂D₅H₂₄FO₄
• Color/Form: Neat
• InChI: InChI=1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1/i4D2,9D,11D2
• InChI key: InChIKey=VWVSBHGCDBMOOT-HFHXZXNHSA-N
• SMILES: [2H]C1=C2C([2H])([2H])C[C@H]3[C@@H]4C[C@@H](C)[C@H](C(=O)C([2H])([2H])O)[C@@]4(C)C[C@H](O)[C@]3(F)[C@@]2(C)C=CC1=O