Dexamethasone

CAS: 50-02-2

Ref. TR-D298800

Product Information

• Name: Dexamethasone
• Synonyms: Betamethasone Imp. A (EP), Dexamethasone Acetate Imp. A (EP), Dexamethasone Sodium Phosphate Imp. A (EP), 9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione, Betamethasone Impurity A, Dexamethasone Acetate Impurity A, Dexamethasone Isonicotinate Impurity A, Dexamethasone Sodium Phosphate Impurity A, (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, (8Xi,11Beta,16Alpha)-9-Fluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione, 1-Dehydro-16α-methyl-9α-fluorohydrocortisone, 16α-Methyl-9α-fluoro-1,4-pregnadiene-11β,17α,21-triol-3,20-dione, 16α-Methyl-9α-fluoro-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione, 16α-Methyl-9α-fluoro-Δ1-hydrocortisone, 16α-Methyl-9α-fluoro-Δ¹-hydrocortisone, 16α-Methyl-9α-fluoroprednisolone, 9-Alpha-Fluoro-11-Beta,17-Alpha,21-Trihydroxy-16-Alpha-Methylpregna-1,4-Diene-3,20-Dione, 9-Alpha-Fluoro-16-Alpha-Methylprednisolone, 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione, 9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregn-1,4-diene-3,20-dione, 9α-Fluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16α-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione, 9α-Fluoro-16α-methyl-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, Adexone, Aeroseb-Dex, Aphtasolon, Aphthasolone, Azium, Calonat, Corsone, Cortisumman, Decacort, Decaderm, Decadron, Decalix, Decasone, Dekacort, Dekort, Delipos, Deltafluorene, Dergramin, Deronil, Desadrene, Desameton, Deseronil, Dexa-Cortidelt, Dexa-Mamallet, Dexa-Scheroson, Dexa-sine, Dexacort, Dexacortal, Dexacortin, Dexadeltone, Dexafarma, Dexalona, Dexaltin, Dexametasona, Dexameth, Dexamethason, Dexamonozon, Dexapolcort, Dexapos, Dexaprol, Dexaratiopharm, Dexason, Dexasone, Dexaven, Dexinoral, Dexium, Dexmethsone, Dexone, Dexonium, Dextelan, Dinormon, Diodex, Etacortilen, Fluormethylprednisolone, Fluormone, Fluorocort, Gammacorten, Gentalipos, HL-Dex, Hexadecadrol, Hexadrol, Isopto-Dex, Loverine, Luxazone, Maxidex, Millicorten, Minidex, Neofordex, Oftan, Oradexon, Ozurdex, Posurdex, Superprednol, Surodex, Visumetazone

Description

Impurity Dexamethasone Sodium Phosphate EP Impurity A
Applications Dexamethasone (Dexamethasone Sodium Phosphate EP Impurity A) is a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.
References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995); Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999); Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999);

• Brand: TRC

Chemical properties

• Molecular weight: 392.46
• Formula: C₂₂H₂₉FO₅
• Color/Form: White To Off-White
• InChI: InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
• InChI key: InChIKey=UREBDLICKHMUKA-KLHOLMHXSA-N
• SMILES: C[C@@H]1C[C@@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO