Dexamethasone 21-Formate

CAS: 50-02-2

Ref. TR-D298910

Product Information

• Name: Dexamethasone 21-Formate
• Synonyms: 2-((8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-Dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl Formate, (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, (8Xi,11Beta,16Alpha)-9-Fluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione, 1-Dehydro-16α-methyl-9α-fluorohydrocortisone, 16α-Methyl-9α-fluoro-1,4-pregnadiene-11β,17α,21-triol-3,20-dione, 16α-Methyl-9α-fluoro-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione, 16α-Methyl-9α-fluoro-Δ1-hydrocortisone, 16α-Methyl-9α-fluoro-Δ¹-hydrocortisone, 16α-Methyl-9α-fluoroprednisolone, 9-Alpha-Fluoro-11-Beta,17-Alpha,21-Trihydroxy-16-Alpha-Methylpregna-1,4-Diene-3,20-Dione, 9-Alpha-Fluoro-16-Alpha-Methylprednisolone, 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione, 9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregn-1,4-diene-3,20-dione, 9α-Fluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16α-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione, 9α-Fluoro-16α-methyl-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, Adexone, Aeroseb-Dex, Aphtasolon, Aphthasolone, Azium, Calonat, Corsone, Cortisumman, Decacort, Decaderm, Decadron, Decalix, Decasone, Dekacort, Dekort, Delipos, Deltafluorene, Dergramin, Deronil, Desadrene, Desameton, Deseronil, Dexa-Cortidelt, Dexa-Mamallet, Dexa-Scheroson, Dexa-sine, Dexacort, Dexacortal, Dexacortin, Dexadeltone, Dexafarma, Dexalona, Dexaltin, Dexametasona, Dexameth, Dexamethason, Dexamonozon, Dexapolcort, Dexapos, Dexaprol, Dexaratiopharm, Dexason, Dexasone, Dexaven, Dexinoral, Dexium, Dexmethsone, Dexone, Dexonium, Dextelan, Dinormon, Diodex, Etacortilen, Fluormethylprednisolone, Fluormone, Fluorocort, Gammacorten, Gentalipos, HL-Dex, Hexadecadrol, Hexadrol, Isopto-Dex, Loverine, Luxazone, Maxidex, Millicorten, Minidex, Neofordex, Oftan, Oradexon, Ozurdex, Posurdex, Superprednol, Surodex, Visumetazone

Description

Applications Dexamethasone 21-Formate is a metabolite of Dexamethasone.
References Minagawa, K., et al.: Steroids, 47, 175 (1986), Murray, G., et al.: Br. J. Clin. Pharmacol., 25, 465 (1988), Ravichandran, K., et al.: Science, 1993, 261, 731 (1993),

• Brand: TRC

Chemical properties

• Molecular weight: 420.47
• Formula: C₂₃H₂₉FO₆
• Color/Form: Neat
• InChI: InChI=1S/C23H29FO6/c1-13-8-17-16-5-4-14-9-15(26)6-7-20(14,2)22(16,24)18(27)10-21(17,3)23(13,29)19(28)11-30-12-25/h6-7,9,12-13,16-18,27,29H,4-5,8,10-11H2,1-3H3/t13-,16+,17+,18+,20+,21+,22+,23+/m1/s1
• InChI key: InChIKey=BNHIJFAJRFEWFF-HOGMHMTRSA-N
• SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC=O