Estimated delivery in United States, on Tuesday 28 May 2024
Product Information
Name:
Dexrazoxane
Synonyms:
- 2,6-Piperazinedione
- 4,4'-[(1S)-1-methyl-1,2-ethanediyl]bis-
- 2,6-Piperazinedione
- 4,4'-(1-methyl-1,2-ethanediyl)bis-
- (S)-
- 2,6-Piperazinedione
- 4,4'-propylenedi-
- (+)- (8CI)
- 4,4'-[(1S)-1-Methyl-1,2-ethanediyl]bis[2,6-piperazinedione]
- (+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane
- See more synonyms
- (S)-(+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane
- ADR 529
- ICRF 187
- NSC 169780
- Savene
- Totect
- Zinecard
CAS:
Description:
Applications Dexrazoxane is a cardioprotective compound against anthracyclines. It is highly protective in reducing anthracycline-induced cardiotoxicity and extravasation injury. It functions by inhibiting topoisomerase II without inducing DNA strand breaks. Dexrazoxane is a + enantiomer of razoxane.
References Walker, D., et al.: Pediatr. Blood Cancer 60,616 (2013); Kang, M., et al.: J. Chemother., 24, 292 (2012); Lipshultz, S., et al.: New England J. Med., 35, 145 (2004)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
268.27
Formula:
C11H16N4O4
Color/Form:
Neat
InChI:
InChI=1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)/t7-/m0/s1
InChI key:
InChIKey=BMKDZUISNHGIBY-ZETCQYMHSA-N
SMILES:
C[C@@H](CN1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-D299050 Dexrazoxane
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