N-Desmethyl rac-14-epi-Dextromethorphan

CAS: 53593-66-1

Ref. TR-D299420

Product Information

• Name: N-Desmethyl rac-14-epi-Dextromethorphan
• Synonyms: (4bS,8aR,9S)-3-Methoxy-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene, (14α)​-​(±)​-3-Methoxymorphinan
• Brand: TRC
• Description: Applications N-Desmethyl rac-14-epi-Dextromethorphan is an intermediate in the synthesis of rac-14-epi-Dextromethorphan (D299440), which is an analog of Dextromethorphan (D299445) which is an antitussive compound showing analgesic properties. Dextromethorphan is used in cough medication formulations.References Church J. et al.: Can J Physiol Pharmacol., 67, 561 (1989); Carliss, R. et al.: Neurotoxicology., 28, 813 (2007)

Chemical properties

• Molecular weight: 257.37
• Formula: C₁₇H₂₃NO
• Color/Form: Neat
• InChI: InChI=1S/C17H23NO/c1-19-13-6-5-12-10-16-14-4-2-3-7-17(14,8-9-18-16)15(12)11-13/h5-6,11,14,16,18H,2-4,7-10H2,1H3/t14-,16-,17-/m1/s1
• InChI key: InChIKey=WPAPSGQWYNPWCZ-UHFFFAOYSA-N
• SMILES: Cc1ccc(C2(c3ccccc3)NC(=O)NC2=O)cc1