rac Diacetolol

CAS: 22568-64-5

Ref. TR-D305200

Product Information

• Name: rac Diacetolol
• Synonyms: Acetamide, N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]-, Acetamide, N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]-, (±)-, Acetanilide, 3'-acetyl-4'-[2-hydroxy-3-(isopropylamino)propoxy]-, DL- (8CI), N-[3-Acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide, (±)-Diacetolol, 1-(4-Acetamido-2-acetylphenoxy)-2-hydroxy-3-isopropylaminopropane, Acetylacebutolol, DL-1-(2-Acetyl-4-acetamidophenoxy)-2-hydroxy-3-isopropylaminopropane, Diacetol, Diacetolol
• Brand: TRC
• Description: Impurity Acebutolol EP Impurity B/ Acebutolol USP RC BApplications The principal metabolite of Acebutolol (A123800) with less β-adrenoceptor blocking potency but greater cardioselectivity (atrial relative to tracheal tissue. Acebutolol EP Impurity B.References Basil, B. et al.: Nouv. Pres, Med., 7, 3258 (1978); Choi, S. et al.: Arch. Pharm. Res., 25, 541 (2002); Basil, B. et al.: Eur. J. Pharmacol., 80, 47 (1982)

Chemical properties

• Molecular weight: 308.37
• Formula: C₁₆H₂₄N₂O₄
• Color/Form: Neat
• InChI: InChI=1S/C16H24N2O4/c1-10(2)17-8-14(21)9-22-16-6-5-13(18-12(4)20)7-15(16)11(3)19/h5-7,10,14,17,21H,8-9H2,1-4H3,(H,18,20)
• InChI key: InChIKey=AWOGXJOBNAWQSF-UHFFFAOYSA-N
• SMILES: CC(=O)Nc1ccc(OCC(O)CNC(C)C)c(C(C)=O)c1