4’,6-Diamidino-2-phenylindole Dihydrochloride

CAS: 28718-90-3

Ref. TR-D416050

Product Information

• Name: 4’,6-Diamidino-2-phenylindole Dihydrochloride
• Synonyms: 2-(4-carbamimidoylphenyl)-1H-indole-6-carboximidamide;dihydrochloride, 1H-Indole-6-carboximidamide, 2-[4-(aminoiminomethyl)phenyl]-, dihydrochloride, 1H-Indole-6-carboximidamide, 2-[4-(aminoiminomethyl)phenyl]-, hydrochloride (1:2), 2-(4-carbamimidoylphenyl)-1H-indole-6-carboximidamide, 2-(4-carbamimidoylphenyl)-1H-indole-6-carboximidamide dihydrochloride, 2-Phenylindole-4',6-dicarboxamidine dihydrohydrochloride (hydrate), 4′,6-Diamidino-2-phenylindole dihydrochloride, 6-Amidino-2-(4-amidinophenyl)indole dihydrochloride, Ccris 8836, FxCycle Violet, Indole-6-carboxamidine, 2-(p-amidinophenyl)-, dihydrochloride

Description

Stability Hygroscopic
Applications A cell-permeable DNA-binding dye. Binds preferentially to DNA rich in adenine and thymine. Used in flow cytometry for measuring nuclear DNA content or for sorting isolated chromosomes.
References Jpeeesen, C, and Nielsen, P.E.: Eur. J. Biochem., 182, 437 (1989), Li,J., et al.: J. Exp. Biol., 200, 1499 (1997), Zaitsev, E.N., and Kowalczykowsi, S.C.: Nucl. Acids Res., 26(2), 650 (1998), Germ, M., et al.: Biochem. Biophys. Res. Commun., 261, 452 (1999),

• Brand: TRC

Chemical properties

• Molecular weight: 350.25
• Formula: C₁₆H₁₅N₅ClH
• Color/Form: Yellow Powder
• InChI: InChI=1S/C16H15N5.2ClH/c17-15(18)10-3-1-9(2-4-10)13-7-11-5-6-12(16(19)20)8-14(11)21-13;;/h1-8,21H,(H3,17,18)(H3,19,20);2*1H
• InChI key: InChIKey=FPNZBYLXNYPRLR-UHFFFAOYSA-N
• SMILES: Cl.Cl.N=C(N)c1ccc(-c2cc3ccc(C(=N)N)cc3[nH]2)cc1