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Desmethyl Nintedanib

CAS:

Ref. TR-D422370

25mg
1,712.00€
Desmethyl Nintedanib
TRC

Product Information

Name:Desmethyl Nintedanib
Controlled Product
Synonyms:
  • Nintedanib Impurity G
  • 2,3-Dihydro-3-[[[4-[[(4-methyl-1-piperazinyl)acetyl]amino]phenyl] amino]phenylmethylene]-2-oxo-methyl Ester-1H-indole-6-carboxylic Acid
  • (Z)-Methyl 3-(((4-(2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
Brand:TRC
Description:Applications Desmethyl Nintedanib is an impurity of Intedanib (I666650), which is an antitumor agent. Desmethyl Nintedanib was used in the study of synthesizing indolinones as triple angiokinase inhibitors.References Roth, G., et al.: J. Med. Chem., 52, 4466 (2009);
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Chemical properties

Molecular weight:525.6
Formula:C30H31N5O4
Color/Form:Neat
InChI:InChI=1S/C30H31N5O4/c1-34-14-16-35(17-15-34)19-26(36)31-22-9-11-23(12-10-22)32-28(20-6-4-3-5-7-20)27-24-13-8-21(30(38)39-2)18-25(24)33-29(27)37/h3-13,18,33,37H,14-17,19H2,1-2H3,(H,31,36)
InChI key:InChIKey=MJBOSKJANLJEQK-DQSJHHFOSA-N
SMILES:COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(NC(=O)CN2CCN(C)CC2)cc1)c1ccccc1

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