Product Information
Name:1,2-Dibromo-4,5-dimethylbenzene
Controlled Product
Synonyms:
- 4,5-Dibromo-1,2-xylene
- 4,5-Dibromo-o-xylene
Brand:TRC
Description:Applications 1,2-Dibromo-4,5-dimethylbenzene is used as a reagent in the synthesis of Thalidomide (T338850); an inhibitor of FGF-induced angiogenesis and replication of human immunodeficiency virus type 1. Also a teratogenic sedative and immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma.References Chen, J., et al.: Org. Biomol. Chem., 12, 5578 (2014); D’Amato, r.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 4082 (1994); Makonkawkeyoon, S., et al.: Proc. Natl. Acad. Sci. USA, 90, 5974 (1993); Schumacher, H., et al.: J. Pharmacol. Exp. Therap., 160, 189 (1968)
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Chemical properties
Molecular weight:263.96
Formula:C8H8Br2
Color/Form:Neat
InChI:InChI=1S/C8H8Br2/c1-5-3-7(9)8(10)4-6(5)2/h3-4H,1-2H3
InChI key:InChIKey=BCIDDURGCAHERU-UHFFFAOYSA-N
SMILES:Cc1cc(Br)c(Br)cc1C
Technical inquiry about: 1,2-Dibromo-4,5-dimethylbenzene
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