2,3-Dichlorobenzoic Acid-13C,d3

CAS: 50-45-3

Ref. TR-D431951

Product Information

• Name: 2,3-Dichlorobenzoic Acid-13C,d3
• Synonyms: 2,3-dichloro-4,5,6-trideuteriobenzoic acid, 2,3-Dichlorbenzoesure, 2,3-Dichloro-Benzoicaci, 2,3-Dichlorobenzoate, 2,3-Dichlorobenzoic, 2,3-Dichlorobenzoicacid, Benzoic acid, 2,3-dichloro-, Rarechem Al Bo 0323, Timtec-Bb Sbb003641

Description

Applications 2,3-Dichlorobenzoic Acid-13C,d3 is an intermediate in synthesizing Lamotrigine-13C3,d3 (L173253), an isotopically labelled Lamotrigine (L173250), an anticonvulsant. Inhibits glutamate release, possible through inhibition of Sodium, Potassium and Calcium currents. Used in treatment of bipolar depression.
References Miller, A.A., et al.: Epilepsia, 27, 483 (1986); Grunze, et al.: Neuropsychobiology, 38, 131 (1998); Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999)

• Brand: TRC

Chemical properties

• Molecular weight: 195.023
• Formula: CC₆D₃HCl₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C7H4Cl2O2/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3H,(H,10,11)/i1D,2D,3D,7+1
• InChI key: InChIKey=QAOJBHRZQQDFHA-PAKQKFEYSA-N
• SMILES: [2H]c1c([2H])c(Cl)c(Cl)c([13C](=O)O)c1[2H]