3-(Dimethylphenylsilyl)-cyclobutanone
CAS:
Ref. TR-D432053
1g
331.00€
250mg
115.00€
500mg
188.00€
Product Information
Name:3-(Dimethylphenylsilyl)-cyclobutanone
Controlled Product
Synonyms:
- 3-(Dimethyl(phenyl)silyl)cyclobutanone
Brand:TRC
Description:Applications 3-(Dimethylphenylsilyl)-cyclobutanone is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3β inhibitors as anticancer agents.References Choi, M.J., et al.: Bull. Korean. Chem. Soc., 32, 2015 (2011); Otani, M., et al.: Bioorg. Med. Chem. Lett.. 20, 4259 (2010); Jhan, Y.H., et al.: Tetrahedron. Lett., 54, 1155 (2013); Hsieh, J.C., et al.: Org. Biomolec. Chem., 10, 6404 (2012);
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Chemical properties
Molecular weight:204.34
Formula:C12H16OSi
Color/Form:Neat
InChI:InChI=1S/C12H16OSi/c1-14(2,12-8-10(13)9-12)11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3
InChI key:InChIKey=UCLQUAUTIGIDGZ-UHFFFAOYSA-N
SMILES:C[Si](C)(c1ccccc1)C1CC(=O)C1
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