cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol

CAS: 61397-58-8

Ref. TR-D435930

Product Information

• Name: cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol
• Synonyms: (2R,4S)-rel-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol, 1,3-Dioxolane-4-methanol, 2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-, cis-, rel-(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol, [(2RS,4SR)-2-(2,4-Dichlorophenyl)-2-(1-Himidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methanol
• Brand: TRC
• Description: Applications cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol is a Ketoconazole (K186000) fragment that may have modulatory activity on the large conductance calcium-activated potassium channel (BKCa).References Power, E.C. et al.: Bioorg. Med. Chem., 16, 887 (2006); Heeres, J. et al.: J. Med. Chem., 22, 1003 (1979)

Chemical properties

• Molecular weight: 329.18
• Formula: C₁₄H₁₄Cl₂N₂O₃
• Color/Form: Neat
• InChI: InChI=1S/C14H14Cl2N2O3/c15-10-1-2-12(13(16)5-10)14(8-18-4-3-17-9-18)20-7-11(6-19)21-14/h1-5,9,11,19H,6-8H2/t11-,14-/m0/s1
• InChI key: InChIKey=VJZJGRMLFMJRGG-FZMZJTMJSA-N
• SMILES: OC[C@H]1CO[C@](Cn2ccnc2)(c2ccc(Cl)cc2Cl)O1