5,6-Dichloropurine-1-(2,3,5-tri-O-acetyl-Beta-D-ribofuanosyl)-1H-benzimidazole

CAS: 443678-71-5

Ref. TR-D435935

Product Information

• Name: 5,6-Dichloropurine-1-(2,3,5-tri-O-acetyl-Beta-D-ribofuanosyl)-1H-benzimidazole
• Synonyms: 5,6-Dichloro-1-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-1H-benzimidazole
• Brand: TRC

Description

Applications A protected inhibitor of RNA synthesis (causes premature termination of transcription).
References Braedlye, J. and Sporns, O.: Brain Res., 815, 140 (1999), Ljungman, M., et al.: Oncogene, 18, 583 (1999), Roele, R.H., et al.: Oncogene, 18, 5765 (1999)

Chemical properties

• Molecular weight: 445.25
• Formula: C₁₈H₁₈Cl₂N₂O₇
• Color/Form: Neat
• InChI: InChI=1S/C18H18Cl2N2O7/c1-8(23)26-6-15-16(27-9(2)24)17(28-10(3)25)18(29-15)22-7-21-13-4-11(19)12(20)5-14(13)22/h4-5,7,15-18H,6H2,1-3H3/t15-,16-,17-,18-/m1/s1
• InChI key: InChIKey=LAILZPSFJJOYLV-BRSBDYLESA-N
• SMILES: CC(=O)OC[C@H]1O[C@@H](n2cnc3cc(Cl)c(Cl)cc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O