3,7-Dichloro-10,11-dihydro-5H-dibenzo[b,f]azepine

CAS: 13080-74-5

Ref. TR-D438128

Product Information

• Name: 3,7-Dichloro-10,11-dihydro-5H-dibenzo[b,f]azepine
• Synonyms: 3,7-Dichloro-10,11-dihydro-5H-dibenz[b,f]azepine
• Brand: TRC

Description

Applications 3,​7-​Dichloro-​10,​11-​dihydro-​5H-​dibenzo[b,​f]​azepine is an intermediate in the preparation of Dichloroimipramine Hydrochloride (D434845), the analog of Imipramine Hydrochloride (I465980), a tricyclic antidepressant.
References Wood, M.D., et al.: Neuropharmacology, 26, 1081 (1987), Casis, O., et al.: J. Cardiovasc. Pharmacol., 32, 521 (1998), Linner, L., et al.: Biol. Psychiatry, 46, 766 (1999), Teschemacher, et al.: Br. J. Pharmacol., 128, 479 (1999);

Chemical properties

• Molecular weight: 264.15
• Formula: C₁₄H₁₁Cl₂N
• Color/Form: Neat
• InChI: InChI=1S/C14H11Cl2N/c15-11-5-3-9-1-2-10-4-6-12(16)8-14(10)17-13(9)7-11/h3-8,17H,1-2H2
• InChI key: InChIKey=RRRKOLZRCMHJSN-UHFFFAOYSA-N
• SMILES: Clc1ccc2c(c1)Nc1cc(Cl)ccc1CC2